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Clinician's Pocket Reference: The Scut Monkey, 11e
Acetaminophen + Butalbital ± Caffeine (Fioricet, Medigesic, Repan, Sedapap-10, Two-Dyne, Triaprin, Axocet, Phrenilin Forte) [C-III]
Topics Discussed: butalbital/acetaminophen/caffeine.
Excerpt:
"Uses: *Tension HA,* mild pain Action: Nonnarcotic analgesic w/barbiturate Dose: 1–2 tabs or caps PO
q4/6h PRN;  in renal/hepatic
impair; 4 g/24 h APAP max Caution: [D, +] Alcoholic
liver Dz Contra: G6PD deficiency Supplied: Caps Medigesic,
Repan, Two-Dyne: butalbital 50 mg, caffeine 40 mg, + APAP
325 mg. Caps Axocet, Phrenilin Forte: butalbital
50 mg + APAP 650 mg; Triapin: butalbital
50 mg + APAP 325 mg. Tabs Medigesic,
Fioricet, Repan: butalbital 50 mg, caffeine 40 mg, + APAP
325 mg; Phrenilin: butalbital 50 mg + APAP
325 mg; Sedapap-10: butalbital 50 mg + APAP
650 mg SE: Drowsiness, dizziness, "hangover" effect Notes: Butalbital habit-forming; avoid
EtOH..."
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