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Clinician's Pocket Reference: The Scut Monkey, 11e
The Left Shift
Sections: Left Shift:, Right Shift:.
Topics Discussed: hematology; hematology procedure; neutrophil.
Excerpt:"The degree of nuclear lobulation of PMNs indicates cell age.
A predominance of immature cells with only one or two nuclear lobes
separated by a thick chromatin band is called a "shift
to the left." Conversely, a predominance of cells
with four nuclear lobes is called a "shift
to the right." (For historical information, left and
right designations come from the formerly used manual lab counters,
in which the keys for entering stabs were located on the left of
the keyboard.) As a rule, 55–80% of PMNs have
two to four lobes. More than 20 five-lobed cells/100 WBCs
suggests megaloblastic anemia, a six- or seven-lobed poly being
diagnostic.Bacterial infection, toxemia, hemorrhage, myeloproliferative
disorders..."
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