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Harrison's Principles of Internal Medicine, 17e | Part Six: Oncology and Hematology > Section 1: Neoplastic Disorders > | Chapter 94. Soft Tissue and Bone Sarcomas and Bone Metastases Sections: Soft Tissue and Bone Sarcomas and Bone Metastases: Introduction, Soft Tissue Sarcomas, Bone Sarcomas, Tumors Metastatic to Bone, Further Readings, Bibliography.
Excerpt:
"Sarcomas are rare (<1% of all malignancies) mesenchymal
neoplasms that arise in bone and soft tissues. These tumors are
usually of mesodermal origin, although a few are derived from neuroectoderm,
and they are biologically distinct from the more common epithelial
malignancies. Sarcomas affect all age groups; 15% are found
in children <15 years and 40% occur after age 55. Sarcomas
are one of the most common solid tumors of childhood and are the
fifth most common cause of cancer deaths in children. Sarcomas may
be divided into two groups, those derived from bone and those derived
from soft tissues...."
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