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Hurst's The Heart, 12e Evaluation of Coronary Artery Disease Sections: Evaluation of
Coronary Artery Disease, Detection
of Coronary Artery Calcification, Multirow
Detector Computed Tomography Compared to Electron Beam Computed
Tomography, Coronary
Artery Calcification and Atherosclerotic Plaque Burden, Coronary
Artery Calcification and Stenosis Severity, Coronary
Artery Calcification and Myocardial Ischemia, Detection of
Subclinical CAD and Stress Testing, Coronary Artery
Calcification and Ischemic Burden, Coronary
Artery Calcification: Prognostic Implications, Risk-Factor
Analysis, Tracking
Changes in Coronary Artery Calcification, Coronary Artery
Calcification Reproducibility, Distinguishing
Ischemic from Nonischemic Conditions with Computed Tomography. Topics Discussed: cardiac ct; cardiomyopathy; coronary arteriosclerosis; coronary artery calcium; coronary heart disease risk; coronary plaque; coronary stenosis; exercise stress test; ischemic heart disease; silent myocardial ischemia.
Excerpt:
"The standard EBCT imaging protocol is to acquire 40 consecutive
3-mm-thick images at a rate of 100 msec per image from the base
of the heart to just below the carina. Images are obtained at end-inspiration,
with ECG triggering typically at 80 percent of the R-R interval
(end-diastole). Image pixel size using a 512 x 512
reconstruction matrix is 0.26 or 0.34 mm2 based on a 26-
or 30-cm field of vision, respectively.Noninvasive techniques, such as exercise treadmill testing and
myocardial perfusion imaging, can identify patients with coronary
atherosclerosis. However, unlike EBCT, which can detect coronary
atherosclerosis at its earliest stages, these techniques can identify
only patients with advanced CAD who manifest myocardial ischemia.
Although the presence and extent of ischemia can accurately identify
asymptomatic individuals at high risk for cardiac events53,54,59 (Fig. 2020), the very low prevalence
of a positive test result (<5 percent) precludes the use of these
methodologies as primary screening tests for the early detection
and treatment of CAD.Traditional risk-factor analysis is commonly used to identify
individuals who are at increased..."
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