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Adams and Victor's Principles of Neurology, 9e
Other Hypothalamic Syndromes
Sections: Other Hypothalamic
Syndromes, Precocious Puberty, Adiposogenital
Dystrophy (Froehlich Syndrome), Hypothalamic
Disorders Associated with Alterations in Weight, Anorexia Nervosa
and Bulimia, Abnormalities
of Growth, Disturbances
of Temperature Regulation, Cardiovascular
Disorders with Hypothalamic Lesions, Gastric Hemorrhage, "Neurogenic" Pulmonary
Edema, Disorders of
Consciousness and Personality, Periodic Somnolence
and Bulimia (Kleine-Levin Syndrome).
Topics Discussed: acromegaly; anorexia nervosa; body temperature; bulimia nervosa; cardiovascular disorders; consciousness disorders; diencephalic syndrome; fever; froehlich syndrome; gastric hemorrhage; growth disorders; growth retardation; hypothalamic tumor; hypothalamus; hypothermia, natural; kleine-levin syndrome; malignant hyperthermia due to anesthesia; neuroendocrine disease or syndrome; neurogenic pulmonary edema; personality disorder; poikilothermia; precocious puberty; temperature regulation disorder.
Excerpt:
"Apart from DI and SIADH, there are a variety of other special
clinical phenomena resulting from disease of the hypothalamus. These
usually occur not in isolation but in various combinations, comprising
a number of rare, but well-characterized, syndromes.This term refers to the abnormally early onset of androgen secretion
and spermatogenesis in boys and of estrogen secretion and cyclic
ovarian secretion in girls. It is associated with the premature development
of secondary sexual characteristics. The occurrence of precocious
puberty always calls for a neurologic as well as an endocrine investigation.
In the male, one searches for evidence of a teratoma of the pineal
gland or mediastinum or an androgenic tumor of the testes or adrenals. In
the female with early development of secondary sexual characteristics
and menstruation, one seeks other evidence of hypothalamic disease,
as well as an estrogen-secreting ovarian tumor...."
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