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Fitzpatrick's Color Atlas & Synopsis of Clinical Dermatology, 6e | Part I. Disorders Presenting in the Skin and Mucous Membranes > | Section 5. Miscellaneous Epidermal Disorders Sections: Acanthosis Nigricans (AN), Acanthosis Nigricans (AN) Picture Gallery, Grover Disease (GD), Grover Disease (GD) Picture Gallery, Pityriasis Rubra Pilaris (PRP), Pityriasis Rubra Pilaris (PRP) Picture Gallery, Disseminated Superficial Actinic Porokeratosis (DSAP), Porokeratosis (PK) Picture Gallery, Darier Disease (DD) Picture Gallery. Excerpt:"No associated endocrine disorder.Type 1: during childhood or puberty; other types dependent on associated conditions.All types of AN: Darkening of pigmentation, skin appears dirty (Fig. 5-1). As skin thickens, appears velvety; skin lines accentuated; surface becomes rugose, mammillated. Type 3: velvety patch on inner, upper thigh at site of chafing; often has many skin tags in body folds and neck. Type 5: hyperkeratosis and hyperpigmentation more pronounced (see Fig. 18-16). Hyperkeratosis of palms/soles, with accentuation of papillary markings: "Tripe hands" (see Fig. 18-18), involvement of oral mucosa and vermilion border of lips (see Fig. 18-17).Most commonly, axillae; (Fig. 5-1), neck (back, sides) also, groins, anogenitalia, antecubital fossae, knuckles, submammary, umbilicus.Dark thickened flexural skin: Confluent and reticulated papillomatosis (Gougerot-Carteaud syndrome), pityriasis versicolor, X-linked ichthyosis, retention hyperkeratosis, nicotinic acid ingestion.Rule out diabetes mellitus; metabolic syndromeRare.Usually in the first or second decade, males and females equally affected.Multiple..."
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