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Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e
| Section I. General Principles > |
Chapter 2. Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination
Sections: Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination: Introduction, Physicochemical Factors in Transfer of Drugs Across Membranes, Drug Absorption, Bioavailability, and Routes of Administration, Distribution of Drugs, Excretion of Drugs, Metabolism of Drugs, Clinical Pharmacokinetics, Distribution, Bibliography.
Topics Discussed: pharmacodynamics; pharmacokinetics.
Excerpt:"In order to understand and control the therapeutic action of drugs in the human body, one must know how much drug will reach the site(s) of drug action and when this will occur. The absorption, distribution, metabolism (biotransformation), and elimination of drugs are the processes of pharmacokinetics (Figure 2–1). Understanding and employing pharmacokinetic principles can increase the probability of therapeutic success and reduce the occurrence of adverse drug effects in the body...."
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