|
Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e
| Section II. Neuropharmacology > |
Chapter 11. Agents Acting at the Neuromuscular Junction and Autonomic Ganglia
Sections: Agents Acting at the Neuromuscular Junction and Autonomic Ganglia: Introduction, The Nicotinic Acetylcholine Receptor, Neuromuscular Blocking Agents, Ganglionic Neurotransmission, Ganglionic Stimulating Drugs, Ganglionic Blocking Drugs, Bibliography.
Topics Discussed: autonomic nervous system; drugs affecting neurotransmission; sympathomimetics; adrenergic antagonists; cholinergics; anticholinergics; neuromuscular blocking agents.
Excerpt:"The nicotinic acetylcholine (ACh) receptor mediates neurotransmission postsynaptically at the neuromuscular junction and peripheral autonomic ganglia; in the CNS, it largely controls release of neurotransmitters from presynaptic sites. The receptor is called the nicotinic acetylcholine receptor because both the alkaloid nicotine and the neurotransmitter ACh can stimulate the receptor. Distinct subtypes of nicotinic receptors exist at the neuromuscular junction and the ganglia, and several pharmacological agents discriminate between the receptor subtypes...."
The content above is only an excerpt.
For full access, log into an existing user account below,
purchase an annual subscription, or
purchase a short-term subscription to the complete website.
|
|
|
|
Or
|
|
|
|