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Williams Gynecology
| Section 4 Gynecologic Oncology > |
Chapter 35. Epithelial Ovarian Cancer
Sections: Epithelial Ovarian Cancer: Introduction, Epidemiology and Risk Factors, Prevention, Low-Malignant-Potential Tumors, Epithelial Ovarian Cancer, References.
Topics Discussed: epithelial ovarian cancer; ovarian cancer.
Excerpt:"In the United States, ovarian cancer accounts for more deaths than all other gynecologic malignancies combined. Worldwide each year, 204,000 women are diagnosed, and 125,000 women die from this disease (Sankaranarayanan, 2006). Of these, epithelial ovarian carcinomas comprise 90 to 95 percent of all cases, including the more indolent low-malignant-potential (borderline) tumors (Quirk, 2005). Because of the similarities of primary peritoneal carcinomas and fallopian tube cancers, they are included within this section for simplicity. In general, there is no effective screening test for ovarian cancer and few notable early symptoms. As a result, three quarters of patients have advanced disease when they are diagnosed. Aggressive debulking surgery, followed by platinum-based chemotherapy, usually results in clinical remission. However, up to 80 percent of women will develop a relapse that eventually leads to disease progression and death...."
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