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Harper's Illustrated Biochemistry, 29e
Chapter 33. Metabolism of Purine & Pyrimidine Nucleotides
Sections: Objectives, Biomedical Importance, Purines & Pyrimidines Are Dietarily Nonessential, Biosynthesis of Purine Nucleotides, Inosine Monophosphate (IMP) Is Synthesized from Amphibolic Intermediates, "Salvage Reactions" Convert Purines & Their Nucleosides to Mononucleotides, Hepatic Purine Biosynthesis Is Stringently Regulated, Reduction of Ribonucleoside Diphosphates Forms Deoxyribonucleoside Diphosphates, Biosynthesis of Pyrimidine Nucleotides, The Deoxyribonucleosides of Uracil & Cytosine Are Salvaged, Regulation of Pyrimidine Nucleotide Biosynthesis, Humans Catabolize Purines to Uric Acid, Gout Is a Metabolic Disorder of Purine Catabolism, Other Disorders of Purine Catabolism, Catabolism of Pyrimidines Produces Water-Soluble Metabolites, Overproduction of Pyrimidine Catabolites Is Only Rarely Associated with Clinically Significant Abnormalities, Summary, References.
Topics Discussed: nucleotide structure and function; purine nucleotides; pyrimidine nucleotides.
Excerpt:"After studying this chapter, you should be able to:..."
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