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Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 7e | Section 7. Cardiovascular Disease > | Chapter 64. Occlusive Arterial Disease Sections: Occlusive Arterial Disease: Introduction, Epidemiology, Pathophysiology, Clinical Features, Diagnosis, Treatment, Disposition and Follow-Up, Practice Guidelines, Upper Extremity Ischemia, References. Topics Discussed: arterial occlusive diseases. Excerpt:"Acute limb ischemia secondary to thrombosis or embolism is a
true medical emergency requiring immediate therapy for limb salvage.
The term critical limb ischemia is used when chronic
progressive peripheral arterial disease results in ischemic pain
at rest, ulceration, or gangrene. Despite improvements in the management
of peripheral arterial disease, current 1-year mortality after the
onset of critical limb ischemia is in excess of 25%, and
25% of survivors require amputation.1,2 Diagnosis
of acute limb ischemia is based primarily on findings of a detailed
history and physical examination. Upon diagnosis, urgent involvement
of both the radiologist and vascular surgeon is required in order
to confirm the diagnosis and initiate treatment to restore blood
flow to the affected limb. For a rapid and reliable diagnosis, a
thorough understanding of the pathophysiology, etiology, and clinical
presentation of occlusive arterial disease is required and can help
guide management decisions...."
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