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Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 7e
Chapter 189. Calcium Channel Blockers
Sections: Epidemiology, Pharmacology, Clinical Features, Diagnosis, Treatment, Disposition and Follow-Up, Acknowledgments, References.
Topics Discussed: calcium channel blockers; poisoning by calcium-channel blockers.
Excerpt:"Emergency physicians are familiar with the use of calcium channel blockers for
the treatment of hypertension and angina pectoris, and for control
of ventricular rate in supraventricular dysrhythmias. Less common
uses include prophylactic treatment of migraine headaches and treatment
of arterial vasospasm due to Raynaud disease, esophageal spasm,
and pulmonary hypertension.1 For the last 50 years,
calcium channel blockers have accounted for more poisoning deaths
than any other cardiovascular drug and are the second most common
cause of prescription drug poisoning death. In 2008, the American
Association of Poison Control Centers received reports of 10,398
toxic exposures to calcium channel blockers with 12 fatalities.2..."
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