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Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 7e
Chapter 192. Iron
Sections: Epidemiology, Pharmacology, Pathophysiology, Toxicity, Clinical Features, Diagnosis, Treatment, Disposition and Follow-Up, Acknowledgment, References.
Topics Discussed: iron; iron poisoning; iron toxicity.
Excerpt:"Iron supplements are widely available, particularly in homes
with small children and young women. Children make up the majority
of those with potentially toxic iron exposures, because they may
be attracted to the bright color and sugar coating of the tablets,
iron tablets left over from pregnancy may be present in homes with
toddlers, and iron may not be considered a poison and thus may be
stored unsafely.1–3 Fortunately, most
children remain asymptomatic or develop only minimal toxicity following
exposure. Women of childbearing age are at particular risk for intentional
iron overdose due to the availability of iron and increased stress during
pregnancy and the postnatal period.4 Iatrogenic
iron overdose is rare.5 Unusual circumstances associated
with pediatric iron poisoning include accidental administration
of ferrous sulfate to an infant and purposeful administration of
iron as a means of child abuse.6,7 Those with large
overdoses, or adults with intentional overdose, are at risk of toxicity or
death without aggressive supportive and antidotal therapy...."
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