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Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 7e
Chapter 196. Anticholinergics
Sections: Epidemiology, Pharmacology, Clinical Features, Diagnosis, Treatment, Disposition and Follow-Up, References.
Topics Discussed: anticholinergic agents; anticholinergic syndrome ; anticholinergic toxicity.
Excerpt:"An anticholinergic is a substance that antagonizes the action
of the neurotransmitter acetylcholine. A large number of pharmaceuticals
and substances found in plants possess anticholinergic activity
(Table 196-1). Atropine (D,L-hyoscyamine),
hyoscyamine, and scopolamine (L-hyoscine) are natural alkaloids
that represent prototypical anticholinergic compounds. An important
principle of anticholinergic toxicity is that many substances possess
anticholinergic activity, either as a direct therapeutic effect
or an adverse effect, in addition to their primary or predominant
pharmacologic effect...."
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