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Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 7e
| Section 17. Endocrine Emergencies > |
Chapter 222. Hyperosmolar Hyperglycemic State
Sections: Hyperosmolar Hyperglycemic State: Introduction, Epidemiology, Pathophysiology, Clinical Features, Diagnosis, Treatment, Complications, Disposition and Follow-Up, References.
Topics Discussed: hyperglycemia, hyperosmolar, nonketotic; hyperglycemic hyperosmolar nonketotic coma.
Excerpt:"The hyperosmolar hyperglycemic state (HHS) is characterized by
progressive hyperglycemia and hyperosmolarity typically found in
a debilitated patient with poorly controlled or undiagnosed type
II diabetes mellitus (DM), limited access to water, and commonly,
a precipitating medical event. In view of its frequent association
with concurrent illnesses and prevalence in debilitated patients,
mortality estimates for HHS are significantly higher than diabetic
ketoacidosis (DKA). Readers are likely to encounter a host of nomenclatures
used to describe this disease state that may include the terms hyperosmotic, non-ketotic, hyperglycemic,
and coma. The syndrome does not necessarily include
ketosis and coma. This chapter uses the terminology adopted by the
American Diabetes Association, "Hyperosmolar Hyperglycemic
State (HHS)." ..."
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