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Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 7e
Chapter 172. Atypical Antidepressants, Serotonin Reuptake Inhibitors, and Serotonin Syndrome
Sections: Atypical Antidepressants, Serotonin Reuptake Inhibitors, and Serotonin Syndrome: Introduction, General Principles of Newer Antidepressants, Trazodone, Bupropion, Mirtazapine, Selective Serotonin Reuptake Inhibitors, Serotonin/Norepinephrine Reuptake Inhibitors, Serotonin Syndrome, References.
Topics Discussed: antidepressive agents; antidepressive agents, second-generation; selective serotonin re-uptake inhibitors; serotonin syndrome.
Excerpt:"The newer antidepressants are commonly referred to as atypical, heterocyclic,
or second-generation antidepressants. These
terms distinguish them from the more traditional monoamine oxidase
inhibitors and cyclic antidepressants. This distinction is important,
because newer antidepressants are more selective in their pharmacologic
activity and have a much different clinical presentation in overdose.
As a group, the newer antidepressants are the most popular form
of psychopharmacologic therapy for the treatment of major depression,
obsessive-compulsive disorder, panic disorders, and eating disorders...."
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