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Hurst's The Heart, 13e
| Part 2. Foundations of Cardiovascular Medicine > |
Chapter 5. Normal Physiology of the Cardiovascular System
Sections: Normal Physiology of the Cardiovascular System: Introduction, Cellular Basis of Contraction, Properties of Myocardial Contraction, Cardiovascular Physiology at the Organ Level, Hemodynamics, The Microcirculation, Special Circulations, Integrated Physiology, References.
Topics Discussed: cardiovascular system.
Excerpt:"The principal function of the cardiovascular (CV) system is to deliver oxygen and nutrients to and remove carbon dioxide and wastes from metabolizing tissues. This is accomplished by means of two specialized circulations in series: a low-resistance pulmonary and a high-resistance systemic circulation driven by specialized muscle pumps, the right and left heart (each in turn composed of a thin-walled atrium and thicker-walled ventricle), respectively. Although CV physiology can be understood at a number of hierarchical levels, the complex interplay among the intrinsic properties of the cardiomyocytes and isolated muscle, chamber mechanics, and their modulation by variable cardiac-loading conditions and neurohormonal and renal compensatory mechanisms determines the integrated performance of the CV system. Accordingly, CV physiology will be examined at cellular, isolated muscle, and organ (isolated heart and integrated systems) levels...."
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