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Harrison's Principles of Internal Medicine, 18e | Part 9. Terrorism and Clinical Medicine > | Chapter 221. Microbial Bioterrorism Sections: Microbial Bioterrorism: Introduction, Category A Agents, Category B and C Agents, Prevention and Preparedness, Further Readings. Topics Discussed: bioterrorism; bioterrorism and disaster preparedness. Excerpt:"Descriptions of the use of microbial pathogens as potential weapons of war or terrorism date from ancient times. Among the most frequently cited of such episodes are the poisoning of water supplies in the sixth century b.c. with the fungus Claviceps purpurea (rye ergot) by the Assyrians, the hurling of the dead bodies of plague victims over the walls of the city of Kaffa by the Tartar army in 1346, and the efforts by the British to spread smallpox to the Native American population loyal to the French via contaminated blankets in 1767. Although the use of chemical weapons in wartime took place in the not-too-distant past (Chap. 222), the tragic events of September 11, 2001, followed closely by the mailing of letters containing anthrax spores to media and congressional offices through the U.S. Postal Service, dramatically changed the mindset of the American public regarding both our vulnerability to microbial bioterrorist attacks and the seriousness and intent of the federal government to protect its citizens against future attacks. Modern science has revealed methods of deliberately spreading or enhancing disease in ways not appreciated by our ancestors. The combination of basic research, good medical practice, and constant vigilance will be needed to defend against such atta..."
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