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Harrison's Principles of Internal Medicine, 18e | Part 10. Disorders of the Cardiovascular System > Section 4. Disorders of the Heart > | Chapter 240. Tumors and Trauma of the Heart Sections: Tumors of the Heart, Treatment Myxoma, Traumatic Cardiac Injury, Further Readings. Topics Discussed: heart neoplasms. Excerpt:"Primary tumors of the heart are rare. Approximately three-quarters are histologically benign, and the majority of these tumors are myxomas. Malignant tumors, almost all of which are sarcomas, account for 25% of primary cardiac tumors (Table 240-1). All cardiac tumors, regardless of pathologic type, have the potential to cause life-threatening complications. Many tumors are now surgically curable; thus, early diagnosis is imperative.Cardiac tumors may present with a wide array of cardiac and noncardiac manifestations. These manifestations depend in large part on the location and size of the tumor and are often nonspecific features of more common forms of heart disease, such as chest pain, syncope, heart failure, murmurs, arrhythmias, conduction disturbances, and pericardial effusion with or without tamponade. Additionally, embolic phenomena and constitutional symptoms may occur...."
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