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Contributors


Editors

Valentin Fuster, MD, PhD, FACC, FAHA
Richard Gorlin, MD / Heart Research Foundation
Professor of Cardiology
Director, Mount Sinai Heart
Director, The Zena and Michael A. Wiener Cardiovascular Institute
and Marie-Josée and Henry R. Kravis Center for Cardiovascular Health
The Mount Sinai Medical Center
New York, New York

Robert A. O’Rourke, MD, MACC, MACP, FAHA
Distinguished Professor of Medicine, Emeritus
University of Texas Health Science Center at San Antonio
San Antonio, Texas

Philip Poole-Wilson, MD, FRCP, FESC, FACC, FMedSci
Professor of Cardiology
British Heart Foundation
Simon Marks Chair of Cardiology
Head of Cardiac Medicine
National Heart and Lung Institute
Faculty of Medicine
Imperial College, London, United Kingdom
Honorary Consultant, Royal Brompton and Harefield NHS Trust
London, United Kingdom

Richard A. Walsh, MD, FACC, FAHA
John H. Hord Professor
Chair, Department of Medicine
Case Western Reserve University
Physician-in-Chief
University Hospitals of Cleveland
Cleveland, Ohio

Associate Editors

Spencer B. King III, MD, MACC, FAHA
Professor of Medicine, Emeritus
Emory University School of Medicine
Director of Interventional Cardiology
Fuqua Chair of Interventional Cardiology
Fuqua Heart Center
Piedmont Hospital
Atlanta, Georgia

Ira S. Nash, MD, FACC, FAHA
Vice Chairman for Veterans Affairs
Associate Professor of Medicine
Samuel Bronfman Department of Medicine
Mount Sinai School of Medicine
Chief of Internal Medicine
James J. Peters VA Medical Center
New York, New York

Eric N. Prystowsky, MD, FACC, FAHA
Consulting Professor of Medicine
Duke University Medical Center
Director, Clinical Electrophysiology Laboratory
St. Vincent Hospital
Indianapolis, Indiana

Robert Roberts, MD, FRCP(C), FACC, FAHA
President and CEO
University of Ottawa Heart Institute
Director, The Ruddy Canadian Cardiovascular Genetics Centre
Ottawa, Ontario, Canada

Online Editorial Board

Senior Editors

Richard A. Walsh, MD, FACC, FAHA
John H. Hord Professor
Chair, Department of Medicine
Case Western Reserve University
Physician-in-Chief
University Hospitals of Cleveland

Daniel I. Simon, MD, FACC, FAHA, FSCAI
Chief, Division of Cardiovascular Medicine
Director, Heart & Vascular Institute
University Hospitals Case Medical Center
Herman K. Hellerstein Professor of Cardiovascular Research
Case Western Reserve University School of Medicine

Associate Editors

Brian D. Hoit, MD, FACC, FAHA, FASE
Professor of Medicine and Physiology and Biophysics
Case Western Reserve University
Director, Echocardiography Laboratory
University Hospitals Case Medical Center

James C. Fang, MD, FACC
Clinical Director of Cardiology
Case Western Reserve University
Medical Director of Heart Failure, Transplantation, and Circulatory Assistance
University Hospitals of Cleveland

Marco Costa, MD, PhD, FACC, FSCAI
Professor of Medicine
Director, Invasive Services
Director, Center for Research and Innovation
University Hospitals of Cleveland
Case Western Reserve University

Multimedia Editor

Deepak L. Bhatt, MD, FACC, FAHA, FSCAI, FESC
Chief of Cardiology, VA Boston Healthcare System
Director, Integrated Interventional Cardiovascular Program at Brigham and Women's Hospital and the VA Boston Healthcare System
Senior Investigator, TIMI Study Group
Boston, Massachusetts

Contributors

Jamil A. Aboulhosn, MD
Assistant Clinical Professor of Medicine
David Geffen School of Medicine
Ahmanson/UCLA Adult Congenital Heart Disease Center
Los Angeles, California
Chapter 83

William T. Abraham, MD
Professor of Internal Medicine
The Ohio State University
Director, Divison of Cardiovascular Medicine
Columbus, Ohio
Chapter 26

Masood Akhtar, MD
Clinical Professor of Medicine
University of Wisconsin School of Medicine and Public Health
Milwaukee, Wisconsin
Chapter 42

R. Wayne Alexander, MD, PhD
Chair, Department of Medicine
R. Bruce Logue Professor of Medicine
Emory University Hospital
Atlanta, Georgia
Chapter 7

Charles Antzelevitch, PhD, FACC, FAHA
Professor of Pharmacology
SUNY Health Science Center at Syracuse
Executive Director/Director of Research, Gordon K. Moe Scholar
Masonic Medical Research Laboratory
Utica, New York
Chapter 35

Juan Jose Badimon, PhD, FACC, FAHA
Professor of Medicine
Director
Cardiovascular Biology Research Laboratory
Mount Sinai School of Medicine
New York, New York
Chapter 53

Lina Badimon, PhD, FESC, FAHA
Professor
Director, Cardiovascular Research Center
Hospital de la Santa Creu I Sant Pau
Barcelona, Spain
Chapter 53

Tanvir K. Bajwa, MD, FACC, FSCAI
Director, Cardiac Catheterization Laboratory
Program Director, Interventional Cardiology Fellowship
Clinical Professor of Internal Medicine
Cardiovascular Disease Section
University of Wisconsin Medical School
Milwaukee Clinical Campus
Aurora Sinai Medical Center
Milwaukee Heart Institute
Milwaukee, Wisconsin
Chapter 110

Anton E. Becker, MD, PhD
Professor
Department of Pathology
University of Amsterdam
Amsterdam, The Netherlands
Chapter 34

Emelia J. Benjamin, MD, ScM
Professor of Medicine
Framingham Heart Study
Boston Medical Center
Boston Massachusetts
Chapter 2

Suzanne Benson, Bsc (Hons)
Clinical Nutritionist/Dietician
Department of Nutrition and Dietetics
Adelaide and Meath Hospital
Dublin, Ireland
Chapter 67

Daniel S. Berman, MD
Professor of Medicine
University of California, Los Angeles
Director, Cardiac Imaging
Cedars-Sinai Medical Center
Los Angeles, California
Chapter 19

Gerald J. Berry, MD
Professor of Pathology
Stanford University
Director of Cardiac Pathology
Stanford University Hospital
Stanford, California
Chapter 27

Daniel G. Blanchard, MD
Professor of Medicine
University of California at San Diego School of Medicine
Chief of Clinical Cardiology, UCSD Thornton Hospital
University of California at San Diego Medical Center
San Diego, California
Chapter 16

Wendy M. Book, MD
Assistant Professor of Medicine
Emory University
Director, Emory Adult Congenital Cardiac Program
Emory Clinic—Emory Hospital
Atlanta, Georgia
Chapter 93

Prof. Dr. med Martin Borggrefe, PhD
Direktor, I. Med. Klinik
Universitätsklinikum Mannheim
Mannheim, Germany
Chapter 46

Kenneth L. Brigham, MD
Professor of Medicine
Emory University
Atlanta, Georgia
Chapter 73

Michael R. Bristow, MD, PhD
S. Gilbert Blount Professor of Medicine
Co-Director of University of Colorado Cardiovascular Institute
University of Colorado Health Sciences Center
Denver, Colorado
Chapter 29

Craig S. Broberg, MD, FACC
Assistant Professor
Department of Cardiology and Heart Disease
Oregon Health & Sciences University
Portland, Oregon
Chapter 96

Bruce R. Brodie, MD
Clinical Professor of Medicine
University of North Carolina
Interventional Cardiologist
LeBauer HeartCare
LeBauer Cardiovascular Research Foundation
Moses Cone Heart & Vascular Center
Chapel Hill, North Carolina
Chapter 63

Robert D. Brook, MD
Assistant Professor of Medicine
Division of Cardiovascular Medicine
University of Michigan
Ann Arbor, Michigan
Chapter 104

Ramon Brugada, MD, FACC
Associate Professor of Medicine
University of Montreal
Director, Clinical Cardiovascular Genetics Center
Montreal Heart Institute
Montreal, Quebec, Canada
Chapter 81

Matthew J. Budoff, MD, FACC, FAHA
Associate Professor of Medicine
University of California, Los Angeles School of Medicine
Program Director
Division of Cardiology
Los Angeles Biomedical Research Institute
Torrance, California
Chapter 20

Allen P. Burke, MD
Professor of Pathology
Georgetown University School of Medicine
Deputy Director
CV Path, International Registry of Pathology
Gaithersburg, Maryland
Chapter 57

Hugh Calkins, MD, FACC, FAHA
Professor of Medicine
Professor of Pediatrics
Director of the Arrhythmia Service
and Clinical Electrophysiology Laboratory
Director of the ARVD Program
Johns Hopkins University School of Medicine
Baltimore, Maryland
Chapter 38

Louis R. Caplan, MD
Professor of Neurology
Harvard Medical School
Senior Neurologist
Beth Israel Deaconess Medical Center
Boston, Massachusetts
Chapter 106

Jonathan R. Carapetis, MBBS, Bmed, Cs, FRACP, FAFPMM, PhD
Professor
The University of Melbourne
Counsultant in Pediatric Infectious Diseases
Royal Children's Hospital Melbourne
School of Health Research
Charles Darwin University
Casuarina, Darwin, Australia
Chapter 74

Mark D. Carlson, MD, MA
Chief Medical Officer
Cardiac Rhythm Management Division
St. Jude Medical
Sylmar, California
Chapter 48

Agustin Castellanos, MD, FACC, FAHA
Professor of Medicine
University of Miami Miller School of Medicine
Director, Clinical Electrophysiology
University of Miami/Jackson Memorial Medical Center
Miami, Florida
Chapter 13

Pamela Charney, MD, FACP
Clinical Professor of Medicine
Clinical Associate Professor of Obstetrics & Gynecology and
Women's Health
Albert Einstein College of Medicine
Program Director, Internal Medicine Residency
Norwalk Hospital
Norwalk, Connecticut
Chapter 102

Jonathan M. Chen, MD
Assistant Professor of Cardiothoracic Surgery
Weill Medical College of Cornell University
Director, Pediatric Cardiac Surgery
Cornell Campus, New York
New York Presbyterian Hospital
New York, New York
Chapter 27

Massimo Chiariello, MD
Professor of Cardiology
Department of Clinical Medicine and Cardiovascular Sciences
Chief of Cardiology
Federico II University
Naples, Italy
Chapter 61

John S. Child, MD, FACC
Streisand Professor of Medicine & Cardiology
David Geffen School of Medicine at UCLA
Director, Ahmanson/UCLA Adult Congenital Heart Disease Center
UCLA Medical Center
Los Angeles, California
Chapter 83

Michael B. Clark, MD
Chief Medical Director
Swiss Re Life and Health
Armonk, New York
Chapter 112

Stephen D. Clements Jr., MD
Director, Outpatient Catheterization Laboratory
Department of Cardiology
Emory University School of Medicine
Atlanta, Georgia
Chapter 66

Lynn Clemow, PhD
Assistant Clinical Professor
Department of Medicine
Columbia University College of Physicians and Surgeons
New York, New York
Chapter 113

Jean-Christophe Cornilly, MD
Associate Professor
Imaging Science Laboratories
Mount Sinai School of Medicine
New York, New York
Chapter 22

Rebecca Costello, MD
Deputy Director
Office of Dietary Supplements
National Institutes of Health
Bethesda, Maryland
Chapter 114

Martin R. Cowie, MD, MSc, FRCP
Professor of Cardiology
National Heart & Lung Institute
Imperial College
Honorary Consultant Cardiologist
Royal Brompton Hospital
London, United Kingdom
Chapter 25

Monica Kelly Cowles, MD, MS
Psychiatric Research Fellow
Department of Psychiatry and Behavioral Sciences
Emory University Hospital
Atlanta, Georgia
Chapter 95

Harry Crijns, MD, PhD
Professor and Chairman
Department of Cardiology
University Hospital Maastricht
The Netherlands
Chapter 43

Peter F. Currie, MD, FRCPE
Consultant Cardiologist
Perth Royal Infirmary
Perth, Scotland, United Kingdom
Chapter 92

Ralph B. D'Agostino, Sr., PhD, FAHA
Professor of Mathematical Statistics and Public Health
Boston University
Boston, Massachusetts
Chapter 2

Owais Dar, MBChB, MRCP
Clinical Research Fellow Cardiology
Imperial College London
National Heart and Lung Institute
London, United Kingdom
Chapter 25

Karina W. Davidson, PhD
Associate Professor of Medicine & Psychiatry
Department of Medicine
Columbia College of Physicians and Surgeons
Zena and Michael Wiener Cardiovascular Institute
Mount Sinai School of Medicine
New York, New York
Chapter 113

James A. de Lemos, MD
J. Fred Schoellkopf Chair in Cardiology Research
University of Texas Southwestern Medical Center
Director, Coronary Care Unit
Parkland Memorial Hospital
Dallas, Texas
Chapter 59

Arjun Deb, MD
Fellow, Division of Cardiovascular Diseases
Duke University Medical Center
Durham, North Carolina
Chapter 10

Santo Dellegrottaglie, MD, PhD
Post-Doctoral Clinical Fellow
Institute of Cardiology
Federico II University of Naples
Naples, Italy
Instructor of Medicine (Adjunct)
Cardiovascular CT/MRI Clinical Program
The Zena and Michael A. Wiener Cardiovascular Institute
The Marie-Josée and Henry R. Kravis Center for Cardiovascular Health
The Mount Sinai Medical Center
New York, New York
Chapter 61

Louis J. Dell’Italia, MD
Professor of Medicine
Center for Heart Failure Research
University of Alabama at Birmingham
School of Medicine
Birmingham VA Medical Center
Birmingham, Alabama
Chapter 76

Anthony N. DeMaria, MD, MACC, FAHA
Professor of Medicine
Director, The Sulpizie Family Cardiovascular Center
University of California at San Diego
San Diego, California
Chapter 16

Christophe Depre, MD, PhD
Associate Professor
Department of Cell Biology and Molecular Medicine
University of Medicine and Dentistry of New Jersey
New Jersey Medical School
Newark, New Jersey
Chapter 54

Roberto De Vogli, PhD, MPH
Lecturer
International Institute for Society and Health
Department of Epidemiology and Public Health
University College London
London, England
Chapter 115

Thomas F. Dodson, MD
Professor of Surgery
Emory University School of Medicine
Associate Chairman
Department of Surgery
Division of Vascular Surgery
Atlanta, Georgia
Chapter 109

John S. Douglas, Jr, MD, FACC
Professor of Medicine (Cardiology)
Director, Interventional Cardiology
Director, Cardiac Catheterization Laboratory
Emory University School of Medicine
Emory University Hospital
Atlanta, Georgia
Chapters 62, 64

Prof. Dr. med. Helmut Drexler, MD
Professor of Medicine
Department of Cardiology and Angiology
Medical School Hannover
Hannover, Germany
Chapter 10

Victor Dzau, MD
James B. Duke Professor of Medicine
Duke University Medical Center
Durham, North Carolina
Chapter 10

Kim A. Eagle, MD
Albion Walter Hewlett Professor of Internal Medicine
University of Michigan
Clinical Director of the Cardiovascular Center
University of Michigan Health System
Ann Arbor, Michigan
Chapter 86

William D. Edwards, MD
Professor of Pathology
Mayo College of Medicine
Staff Consultant, Anatomic Pathology
Mayo Clinic
Rochester, Minnesota
Chapter 3

John A. Elefteriades, MD
Professor of Surgery
Department of Cardiothoracic Surgery
Yale University School of Medicine
Chief, Cardiothoracic Surgery
Yale University School of Medicine
New Haven, Connecticut
Chapter 105

Kenneth A. Ellenbogen, MD
Kontos Professor of Cardiology
VCU School of Medicine
Vice-Chairman of Cardiology
Medical College of Virginia
Richmond, Virginia
Chapter 40

Gregory Engel, MD
Division of Cardiovascular Medicine
Stanford University School of Medicine
Staff Cardiologist
Veterans Affairs Palo Alto Health Care System
Palo Alto, California
Chapter 14

N.A. Mark Estes III, MD
Professor of Medicine
Director
Tufts New England Medical Center
Boston, Massachusetts
Chapter 100

Michael S. Ewer, MD, JD, MPH, LLM
Professor of Medicine
The University of Texas M.D. Anderson Cancer Center
Houston, Texas
Chapter 89

Gordon A. Ewy, MD, FACC, FAHA
Professor of Medicine (Cardiology)
University of Arizona College of Medicine
Chief, Section of Cardiology
Director, Sarver Heart Center
Arizona Health Sciences Center
Tucson, Arizona
Chapter 50

Erling Falk, MD, PhD
Professor
University of Aarhus
Department of Cardiology
Aarhus University Hospital
Aarhus, Denmark
Chapter 52

Noeleen Fallon, BSc
Clinical Nurse Manager
Department of Cardiac Rehabilitation
Adelaide and Meath Hospital
Dublin, Ireland
Chapter 67

Michael E. Farkouh, MD, MSc
Clinical Coordinating Center
Mount Sinai School of Medicine
New York, New York
Chapter 90

Michael D. Faulx, MD
Assistant Professor of Medicine
Cleveland Clinic Lerner College of Medicine
Staff
Case Western Reserve University
The Cleveland Clinic
Cleveland, Ohio
Chapter 94

Zahi A. Fayad, PhD
Associate Professor of Radiology and Medicine
Director, Imaging Science Laboratories
Mount Sinai School of Medicine
New York, New York
Chapter 22

Peter F. Fedullo, MD
Professor of Medicine
Director, Medical Intensive Care Unit
Division of Pulmonary and Critical Care Medicine
University of California at San Diego Medical Center
San Diego, California
Chapter 72

Gerald F. Fletcher, MD
Professor of Medicine, Cardiovascular
Mayo Clinic College of Medicine
Preventive Cardiologist
Mayo Clinic Jacksonville
Jacksonville, Florida
Chapter 99

Thomas R. Flipse, MD
Assistant Professor of Medicine
Mayo Clinic College of Medicine
Jacksonville, Florida
Chapter 99

Richard I. Fogel, MD
Clinical Electrophysiologist
The Heart Center of Indiana
Indianapolis, Indiana
Chapter 36

Gary S. Francis, MD
Professor of Medicine
Cleveland Clinic Lerner College of Medicine
Case Western Reserve University
Staff, Department of Cardiovascular Medicine
The Cleveland Clinic
Cleveland, Ohio
Chapters 24, 94

William T. Friedewald, MD
Clinical Professor
Columbia University
New York, New York
Chapter 112

Victor F. Froelicher, MD
Professor of Medicine
Division of Cardiovascular Medicine
Stanford University
Director of ECG/Exercise Laboratory
Palo Alto Veterans Affairs Medical Center
Palo Alto, California
Chapter 14

David R. Fulton, MD
Associate Professor of Pediatrics
Harvard Medical School
Chief, Cardiology Outpatient Services
Children's Hospital Boston
Boston, Massachusetts
Chapter 82

Valentin Fuster, MD, PhD, FACC, FAHA
Richard Gorlin, MD / Heart Research Foundation
Professor of Cardiology
Director, Mount Sinai Heart
Director, The Zena and Michael A. Wiener Cardiovascular
Institute and Marie-Josée and Henry R. Kravis Center for
Cardiovascular Health
The Mount Sinai Medical Center
New York, New York
Chapters 22, 52, 53, 56, 90

Guido Germano, PhD
Professor of Medicine
UCLA School of Medicine
Director, Artificial Intelligence in Medicine Program
Cedars-Sinai Medical Center
Los Angeles, California
Chapter 19

Bernard J. Gersh, MBChB, DPhil, FRCP, PhD (Hon Causa)
Professor of Medicine
Division of Cardiovascular Diseases
Mayo Clinic
Rochester, Minnesota
Chapters 60, 61

Antony H. Gershlick, BSc, MBBS
Consultant Cardiologist
Hon Senior Lecturer
Department of Cardiology
University Hospitals of Leicester
Leicester, United Kingdom
Chapter 61

Gary Gerstenblith, MD
Professor of Medicine
Department of Medicine
The Johns Hopkins University School of Medicine
Johns Hopkins Hospital
Baltimore, Maryland
Chapter 101

Edward M. Gilbert, MD
Professor
Department of Cardiology
University of Utah Health Sciences Center
Salt Lake City, Utah
Chapter 29

Robert C. Gilkeson, MD
Section Chief, Cardiothoracic Imaging
Department of Radiology
University Hospitals of Cleveland
Cleveland, Ohio
Chapter 15

John Gormley, BSc (Hons), DPhil
Lecturer
Department of Physiotherapy
School of Medicine
Trinity College of Dublin
Dublin, Ireland
Chapter 67

Ian Graham, FRCPI, FESC
Consultant Cardiologist
Adelaide & Meath Hospital
Professor of Cardiovascular Medicine
Trinity College
Professor of Preventive Cardiology
Royal College of Surgeons in Ireland
Tallaght, Dublin
Ireland
Chapter 67

Joey P. Granger, Ph.D
Billy S. Guyton Distinguished Professor
Professor of Physiology and Medicine
Department of Physiology & Biophysics
Department of Medicine
Interim Dean
School of Graduate Studies in the Health Sciences
Center for Excellence in Cardiovascular-Renal Research
University of Mississippi Medical Center
Jackson, Mississippi
Chapter 69

Kathy K. Griendling, PhD
Professor of Medicine
Vice Chair for Faculty Development
Emory University
Division of Cardiology, Emory University
Atlanta, Georgia
Chapter 7

Garrett J. Gross, PhD
Professor
Department of Pharmacology and Toxicology
Medical College of Wisconsin
Milwaukee, Wisconsin
Chapter 54

Blair P. Grubb, MD
Professor of Medicine and Pediatrics
The Medical University of Ohio
Director, Cardiac Electrophysiology Service
University Medical Center
Toledo, Ohio
Chapter 48

Scott M. Grundy, MD, PhD
Director, Center for Human Nutrition
Professor of Internal Medicine
Departments of Clinical Nutrition and
Internal Medicine
University of Texas Southwestern Medical Center at Dallas
Dallas, Texas
Chapters 51, 91

Gary L. Grunkemeier, PhD
Director
Medical Data Research Center
Portland, Oregon
Chapter 79

Sanjaya Gupta, MD
Chief Resident
Department of Medicine
Case Western Reserve University
University Hospitals of Cleveland
Cleveland, Ohio
Chapter 31

Anjan Gupta, MD, FACC, FSCAI
Associate Director, Cardiology Fellowship Program
University of Wisconsin Medical School Milwaukee
Milwaukee, Wisconsin
Chapter 110

Rory Hachamovitch, MD, MSc, FACC
Voluntary Faculty
Los Angeles County
USC Medical Center
Los Angeles, California
Chapter 19

Saptarsi M. Haldar, MD
Assistant Professor of Medicine
Case Cardiovascular Research Institute
Case University Medical School and
University Hospitals of Cleveland
Cleveland, Ohio
Chapter 85

Michael E. Hall, MD
Internal Medicine Resident
Department of Physiology & Biophysics
Department of Medicine
Center for Excellence in Cardiovascular-Renal Research
University of Mississippi Medical Center
Jackson, Mississippi
Chapter 69

John E. Hall, PhD
Arthur C. Guyton Professor and Chair
Department of Physiology and Biophysiology
Associate Vice Chancellor for Research
University of Mississippi Medical Center
Jackson, Mississippi
Chapter 69

Jonathan L. Halperin, MD
Robert and Harriet Heilbrunn Professor of Medicine (Cardiology)
Mount Sinai School of Medicine
Director, Clinical Cardiology Services
The Zena and Michael A. Wiener Cardiovascular Institute
The Marie-Josée and Henry R. Kravis Center for Cardiovascular
Health
The Mount Sinai Medical Center
New York, New York
Chapter 105

David G. Harrison, MD
Director, Division of Cardiology
Bernard Marcus Professor of Medicine
Emory University
Atlanta, Georgia
Chapter 7

Ayesha Hasan, MD
Assistant Clinical Professor of Cardiovascular Medicine
Director, Heart Failure Devices Program
Division of Cardiovascular Medicine
The Ohio State University
Columbus, Ohio
Chapter 26

Sean W. Hayes, MD
Assistant Director, Nuclear Cardiology
Cedars-Sinai Medical Center
Los Angeles, California
Chapter 19

Siew Yen Ho, PhD, FRCPath, FESC
Reader in Cardiac Morphology
National Heart & Lung Institute, Imperial College
Honorary Consultant
Royal Brompton Hospital
London, England
Chapter 34

Brian D. Hoit, MD
Professor of Medicine and Phsyiology and Biophysics
Case Western Reserve University
Director, Echocardiography Laboratory
University Hospitals of Cleveland
Cleveland, Ohio
Chapters 4, 31, 84

Borja Ibanez, MD
Research Fellow
Cardiovascular Biology Research Laboratory
Mount Sinai School of Medicine
New York, New York
Chapter 53

Shirley Ingram, RGN, MSc, NFESC
Cardiology Nurse Specialist
Department of Cardiac Rehabilitation
Adelaide and Meath Hospital
Dublin, Ireland
Chapter 67

Alberto Interian Jr., MD
Professor of Medicine
Director, Electrophysiology
Miller School of Medicine
Jackson Memorial Hospital
Director, Arrhythmia Syncope Center
Mercy Hospital
Miami, Florida
Chapter 13

Daniel W. Jones, MD
Vice Chancellor for Health Affairs
Dean, School of Medicine
Langford Professor of Medicine
Professor, Department of Physiology & Biophysics
Department of Medicine
Center for Excellence in Cardiovascular-Renal Research
University of Mississippi Medical Center
Jackson, Mississippi
Chapter 69

Mark E. Josephson, MD, FACC
Chief, Cardiovascular Division
Beth Israel Deaconess Medical Center
Professor of Medicine
Harvard Medical School
Director, Harvard-Thorndike Electrophysiology Institute and
Arrhythmia Service
Boston, Massachusetts
Chapter 49

Ronald J. Kanter, MD
Associate Professor of Pediatrics
Duke University School of Medicine
Director of Pediatric Electrophysiology
Durham, North Carolina
Chapter 47

Samir R. Kapadia, MD
Associate Professor, Department of Medicine
Cleveland Clinic Lerner College of Medicine of Case Western
Reserve University
Staff Physician
The Cleveland Clinic
Cleveland, Ohio
Chapter 107

Joel A. Kaplan, MD
Dean Emeritus, School of Medicine
Former Chancellor, Health Sciences Center
Professor of Clinical Anesthesiology
University of Louisville School of Medicine
Louisville, Kentucky
Professor of Clinical Anesthesiology
University of California San Diego School of Medicine
San Diego, California
Chapter 87

Neeru Kaushik, MD
Senior Fellow in Pediatric Cardiology
Division of Pediatric Cardiology
Department of Pediatrics
University of Pittsburgh School of Medicine
Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania
Chapter 8

Bradley B. Keller, MD
Professor of Pediatrics, Division of Pediatric Cardiology
Department of Pediatrics
University of Pittsburgh School of Medicine
Director, Pediatric Biomedical Innovative Technology
Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania
Chapter 8

Richard E. Kerber, MD
Professor of Medicine
University of Iowa College of Medicine
Staff Physician
University of Iowa Hospitals and Clinics
Iowa City, Iowa
Chapter 45

Morton J. Kern, MD
Professor of Medicine
Associate Chief Cardiology
University of California, Irvine
Irvine, California
Chapter 17

Han W. Kim, MD
Associate in Medicine
Attending Physician
Duke Cardiovascular Magnetic Resonance Center
Duke University Medical Center
Durham, North Carolina
Chapter 21

Michael C. Kim, MD
Assistant Professor of Medicine
Mount Sinai School of Medicine
Director, Coronary Care Unit
The Mount Sinai Medical Center
New York, New York
Chapter 56

Raymond J. Kim, MD, FACC
Associate Professor of Medicine and Radiology
Co-Director, Duke Cardiovascular Magnetic Resonance Center
Duke University Medical Center
Durham, North Carolina
Chapter 21

Spencer B. King III, MD, MACC, FAHA
Professor of Medicine, Emeritus
Emory University School of Medicine
Director of Interventional Cardiology
Fuqua Chair of Interventional Cardiology
Fuqua Heart Center
Piedmont Hospital
Atlanta, Georgia
Chapters 17, 62

Annapoorna S. Kini, MD, MRCP, FACC
Associate Professor
Mount Sinai School of Medicine
Associate Director, Cardiac Catheterization Laboratory
Mount Sinai Hospital
New York, New York
Chapter 56

Timothy Knilans, MD
Associate Professor of Pediatrics
University of Cincinnati College of Medicine
Director, Clinical Cardiac Electrophysiology and Pacing
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio
Chapter 47

Peter R. Kowey, MD
Professor of Medicine and Clinical Cardiology
Jefferson Medical College
Philadelphia, Pennsylvania
Main Line Health System
Wynnewood, Pennsylvania
Chapter 43

Mitchell W. Krucoff, MD, FACC, FCCP
Professor Medicine/Cardiology
Duke University Medical Center
Director, Cardiovascular Devices Unit
Director, ECG Core Laboratory
Duke Clinical Research Institute
Chapel Hill, North Carolina
Chapter 114

Harlan M. Krumholz, MD, SM
Harold H. Hines, Jr. Professor of Medicine
Yale University School of Medicine
Director, Center for Outcomes Research and Evaluation
Yale New Haven Hospital
New Haven, Connecticut
Chapter 111

Edward G. Lakatta, MD
Professor
The Johns Hopkins University
Director
Laboratory of Cardiovascular Science
Gerontology Research Center
National Institute on Aging Intramural Research Program
National Institutes of Health
Baltimore, Maryland
Chapter 101

E. Clinton Lawrence, MD
Augustus J. McKeloey Professor of Medicine
Emory University School of Medicine
Medical Director of Lung Transplantation
Emory University Hospital
Atlanta, Georgia
Chapter 73

Megan C. Leary, MD
Instructor in Neurology
Harvard Medical School
Co-Director, Inpatient Stroke Service
Beth Israel Deaconess Medical Center
Boston, Massachusetts
Chapter 106

Daniel J. Lenihan, MD
Associate Professor of Medicine
The University of Texas M.D. Anderson Cancer Center
Director, Clinical Research
The University of Texas M.D. Anderson Cancer Center
Department of Cardiology
Houston, Texas
Chapter 89

Tora Leong, MBChB, MRCPI
Senior Research Fellow
Specialist Registrar in Cardiology
Adelaide and Meath Hospital and Trinity College
Dublin, Ireland
Chapter 67

William Lewis, MD
Professor
Department of Pathology
Emory University School of Medicine
Director, Division of Cardiovascular Pathology
Emory Health Care
Atlanta, Georgia
Chapter 92

Mark S. Link, MD
Associate Professor of Medicine
Tufts University School of Medicine
Tufts-New England Medical Center
Boston, Massachusetts
Chapter 100

Brian D. Lowes, MD
Associate Professor of Medicine/Cardiology
University of Colorado
University of Colorado Health Sciences Center
Denver, Colorado
Chapter 29

Bruce W. Lytle, MD
Professor of Surgery
Chairman, Thoracic & Cardiovascular Surgery
The Cleveland Clinic
Cleveland, Ohio
Chapter 65

Vincent Maher, MD, FRCPI
Consultant Cardiologist
Department of Cardiology
Adelaide and Meath Hospital
Tallaght, Ireland
Chapter 67

Giuseppe Maiolino, MD
Research Fellow
Cebzini Medical Center
Chapter 20

Joseph F. Malouf, MD
Professor of Medicine
Mayo Clinic College of Medicine
Consultant, Cardiovascular Diseases
Mayo Clinic
Rochester, Minnesota
Chapter 3

Donna M. Mancini, MD
Professor of Medicine
Columbia University
New York, New York
Chapter 32

Ali J. Marian, MD
Professor of Cardiovascular Genetics and Medicine
Center for Cardiovascular Genetic Research
The Brown Foundation Institute of Molecular Medicine
The University of Texas Health Science Center
Texas Heart Institute at St. Luke's Episcopal Hospital
Houston, Texas
Chapter 81

Daniel Mark, MD, MPH
Professor of Medicine
Duke University Medical Center
Durham, North Carolina
Chapter 114

Roger R. Markwald, PhD
Distinguished University Professor and Chairman
Department of Cell Biology and Anatomy
Director, Cardiovascular Developmental Biology Center
Adjunct Professor of Pediatrics
Department of Pediatrics
Medical University of South Carolina
Charleston, South Carolina
Chapter 8

Sir Michael G. Marmot, MD, PhD, FRCP
Director, International Institute for Society and Health
Head, Department of Epidemiology and Public Health
Professor
University College London
London, England
Chapter 115

Barry J. Maron, MD
Director, Hypertrophic Cardiomyopathy Center
Minneapolis Heart Institute Foundation
Minneapolis, Minnesota
Chapters 28, 100

David J. Maron, MD
Associate Professor of Medicine
Vanderbilt University Medical Center
Division of Cardiovascular Medicine
Nashville, Tennessee
Chapter 51

S. Carolina Masri, MD
Fellow in Cardiovascular Disease
University of Minnesota
Minneapolis, Minnesota
Chapter 103

Tahsin Masud, MD
Associate Professor of Medicine
Renal Division
Department of Medicine
Emory University School of Medicine
Chief of Nephrology
Emory Crawford Lung Hospital
Atlanta, Georgia
Chapter 98

Bongani M. Mayosi, DPhil, FRCP, FACC
Professor of Medicine and Head of Department
Physician-in-Chief
Department of Medicine
Groote Schuur Hospital, Observatory
Cape Town, South Africa
Chapter 74

John H. McAnulty, MD, FACC, FAHA
Professor Emeritus of Medicine
Division of Cardiology
Oregon Health and Sciences University
Good Samaritan Hospital
Portland, Oregon
Chapter 80, 96

William M. McClellan, MD, MPH
Professor of Medicine
Renal Division, Department of Medicine
Emory University School of Medicine
Atlanta, Georgia
Chapter 98

William M. McDonald, MD
Professor
Department of Psychiatry and Behavioral Sciences
Emory University School of Medicine
Atlanta, Georgia
Chapter 95

Elizabeth McNally, MD, PhD
Director, Institute for Cardiovascular Research
Director, Cardiovascular Genetics Laboratory
Professor of Medicine and Human Genetics
The University of Chicago Hospitals
Center for Advanced Medicine
Chicago, Illinois
Chapter 9

Luisa Mestroni, MD
Professor of Medicine/Cardiology
University of Colorado Health Sciences Center
Aurora, Colorado
Chapter 29

James Metcalfe, MD
Professor Emeritus of Medicine
Oregon Health Sciences University
School of Medicine
Portland, Oregon
Chapter 96

Alexander Mittnacht, MD
Assistant Professor
Mount Sinai School of Medicine
Assistant Clinical Attending
Mount Sinai Hospital
New York, New York
Chapter 87

Douglas C. Morris, MD, FACC, FAHA
J. Willis Hurst Professor of Medicine
Emory University School of Medicine
Director, Emory Hurst Center
Emory Clinic
Atlanta, Georgia
Chapter 66

Debabrata Mukherjee, MD
Gill Foundation Professor of Interventional Cardiology
Director of Peripheral Intervention Program
Associate Director for Cardiac Catheterization Laboratories
Division of Cardiovascular Medicine
University of Kentucky
Lexington, Kentucky
Chapter 86

Dominique L. Musselman, MD, MS
Associate Professor
Department of Psychiatry and Behavioral Sciences
Emory University School of Medicine
Atlanta, Georgia
Chapter 95

Robert J. Myerburg, MD
Professor of Medicine and Physiology
American Heart Association Chair in Cardiovascular Research
Division of Cardiology
University of Miami Miller School of Medicine
Miami, Florida
Chapter 13

Deepak G. Nair, MD, MS, MHA, RVT
Vascular Fellow
Department of Surgery
Emory University
Atlanta, Georgia
Chapter 109

Samer S. Najjar, MD
Head, Human Cardiovascular Studies Unit
Laboratory of Cardiovascular Science
Gerontology Research Center
National Institute on Aging Intramural Research Program
National Institutes of Health
Baltimore, Maryland
Chapter 101

Carlo Napolitano, MD, PhD
Senior Scientist and Research Coordinator
Department of Molecular Cardiology
Fondazione Salvatore Maugeri
Pavia, Italy
Chapter 33

Ira S. Nash, MD, FACC, FAHA
Vice Chairman for Veterans Affairs
Associate Professor of Medicine
Samuel Bronfman Department of Medicine
Mount Sinai School of Medicine
Chief of Internal Medicine
James J Peters VA Medical Center
New York, New York
Chapter 11

Charles B. Nemeroff, MD, PhD
Reunette W. Harris Professor and Chairman
Department of Psychiatry and Behavioral Sciences
Emory University School of Medicine
Atlanta, Georgia
Chapter 95

Stephen J. Nicholls, MBBS, PhD
Research Associate
The Cleveland Clinic
Associate Director
Intravascular Ultrasound Core Laboratory
The Cleveland Clinic
Cleveland, Ohio
Chapter 18

Rick A. Nishimura, MD, FACC
Judd and Mary Morris Leighton Professor of Cardiovascular Diseases
Professor of Medicine
Mayo Clinic College of Medicine
Consultant, Division of Cardiovascular Diseases
Rochester, Minnesota
Chapter 30

Steven E. Nissen, MD
Interim Chairman
Department of Cardiovascular Medicine of Cleveland Clinic
Cleveland Clinic Foundation
Cleveland, Ohio
Chapter 18

Veronica O’Doherty, MSc, MPhil, BA, RGN
Psychologist
Trinity College Dublin
University College Dublin
Acting Principal Psychologist
Adelaide, Meath and National Children's Hospital
Dublin, Ireland
Chapter 67

Patrick T. O’Gara, MD, FACC, FAHA
Associate Professor of Medicine
Harvard Medical School
Director, Clinical Cardiology
Cardiovascular Division
Brigham and Women's Hospital
Boston, Massachusetts
Chapters 64, 85

Gbenga Ogedegbe, MD, MPH, MS, FAHA
Assistant Professor of Medicine
Columbia University College of Physicians and Surgeons
Assistant Attending Physician
Columbia Presbyterian Medical Center
New York, New York
Chapter 68

Keith R. Oken, MD
Assistant Professor of Medicine
Mayo Clinic College of Medicine
Consultant, Cardiovascular Diseases
Director, Cardiopulmonary Rehabilitation
Jacksonville, Florida
Chapter 99

Jeffrey W. Olin, DO
Professor of Medicine
Mount Sinai School of Medicine
Director, Vascular Medicine
The Mount Sinai Medical Center
New York, New York
Chapter 105

Steve R. Ommen, MD
Associate Professor of Medicine
Mayo Clinic College of Medicine
Consultant, Divison of Cardiovascular Diseases
Department of Internal Medicine
Mayo Clinic
Rochester, Minnesota
Chapter 30

William W. O’Neill, MD, FACC
Director of Cardiology
William Beaumont Hospital
Division of Cardiology
Royal Oak, Michigan
Chapter 63

Robert A. O’Rourke, MD, MACC, MACP, FAHA
Distinguished Professor of Medicine, Emeritus
University of Texas Health Science Center at San Antonio
San Antonio, Texas
Chapters 12, 15, 59, 60, 64, 76, 88

Benzy J. Padanilam, MD, FACC
Faculty, Electrophysiology Fellowship Program
Attending Electrophysiologist
The Care Group
St. Vincent Hospital
Indianapolis, Indiana
Chapter 41

Richard L. Page, MD
Robert A. Bruce Endowed Chair in Cardiovascular Research
Head, Division of Cardiology
University of Washington Medical Center
Seattle, Washington
Chapter 39

Thomas A. Pearson, MD, MPH, PhD
Albert A. Kaisar Professor and Chair
Department of Community & Preventive Medicine
University of Rochester School of Medicine & Dentistry
University of Rochester Medical Center
Rochester, New York
Chapter 51

John Pepper, Mchir, FRCS
Professor
Imperial College, School of Medicine
Consultant Cardiac Surgeon
Royal Brompton Hospital
London, United Kingdom
Chapter 66

Michael X. Pham, MD, MPH
Instructor of Medicine
Stanford University School of Medicine
Medical Director of Heart Failure and Transplantation
VA Palo Alto Health Care System
Stanford, California
Chapter 27

Thomas G. Pickering, MD, DPhil
Assistant Professor of Medicine
Center for Behavioral Cardiovascular Health
Columbia Presbyterian Medical Center
New York, New York
Chapters 68, 113

Ileana L. Piña, MD
Professor of Medicine
Case Western Reserve University
Director, Heart Failure & Cardiac Transplantation
University Hospitals of Cleveland
Cleveland, Ohio
Chapter 94

Sean P. Pinney, MD
Assistant Professor of Medicine
Mount Sinai School of Medicine
Director, Advanced Heart Failure & Cardiac Transplant Program
New York, New York
Chapter 32

David J. Pinsky, MD
J. Griswold Ruth MD and Margery Hopkins Ruth Professor of Internal Medicine
University of Michigan
Ann Arbor, Michigan
Chapter 58

Duane S. Pinto, MD
Assistant Professor of Medicine
Harvard Medical School
Director, Cardiology Fellowship
Beth Israel Deaconess Medical Center
Boston, Massachusetts
Chapter 49

Philip Poole-Wilson, MD, FRCP, FESC, FACC, FMedSci
Professor of Cardiology
British Heart Foundation
Simon Marks Chair of Cardiology
Head of Cardiac Medicine
National Heart and Lung Institute
Faculty of Medicine
Imperial College, London, United Kingdom
Honorary Consultant, Royal Brompton and Harefield NHS Trust
London, United Kingdom
Chapter 24, 26

Michael Poon, MD
Associate Clinical Professor
Department of Cardiology
Mount Sinai School of Medicine
New York, New York
Chapter 20

Silvia G. Priori, MD, PhD
Associate Professor of Cardiology
Department of Cardiology, University of Pavia-Italy
Head of Molecular Cardiology
Fondazione Salvatore Maugeri
Pavia, Italy
Chapter 33

Eric N. Prystowsky, MD, FACC, FAHA
Consulting Professor of Medicine
Duke University Medical Center
Director, Clinical Electrophysiology Laboratory
St. Vincent Hospital
Indianapolis, Indiana
Chapters 36, 37, 41

Shahbudin H. Rahimtoola, MB, FRCP, MACP, MACC, DSc (Hon)
Distinguished Professor
University of Southern California
George C. Griffith Professor of Cardiology
Professor of Medicine
Keck School of Medicine at University of Southern Califonria
Chief Physician
Los Angeles County University of Southern California
Medical Center
Los Angeles, California
Chapters 75, 77, 79, 80

Mahboob Rahman, MD, MS
Associate Professor of Medicine
Case Western Reserve University
Division of Nephrology and Hypertension
University Hospitals of Cleveland
Louis Stokes Cleveland VA Medical Center
Cleveland, Ohio
Chapter 70

Vivek Rajagopal, MD
Clinical Cardiologist
Piedmont Hospital
Atlanta, Georgia
Chapter 107

Sanjay Rajagopalan, MD
Associate Professor of Medicine
Director, MR & CT Program
Mount Sinai School of Medicine
New York, New York
School of Public Health
Department of Internal Medicine
Ohio State University
Columbus, Ohio
Chapter 104

Arash Rashidi, MD
Nephrology and Clinical Hypertension Fellow
Division of Nephrology and Hypertension
University Hospitals Case Medical Center and Metro Health
Medical Center
Case Western Reserve University
Cleveland, Ohio
Chapter 70

Elliot J. Rayfield, MD
Clinical Professor of Medicine
Mount Sinai School of Medicine
Attending Physician
Mount Sinai Hospital
New York, New York
Chapter 90

Wolfgang G. Rehwald, PhD
Senior Scientist
Siemens Medical Solutions
Duke Cardiovascular Magnetic Resonance Center
Duke University Health Systems
Durham, North Carolina
Chapter 21

David L. Reich, MD
Horace W. Goldsmith Professor and Chair
Department of Anesthesiology
Mount Sinai School of Medicine
New York, New York
Chapter 87

Matthew R. Reynolds, MD, MSc
Instructor in Medicine
Harvard Medical School
Associate Director of Electrophysiology
Boston VA Healthcare System
Beth Israel Deaconess Medical Center
Boston, Massachusetts
Chapter 49

Robert T. Rho, MD
Assistant Professor of Medicine
Division of Cardiology
University of Washington School of Medicine
Seattle, Washington
Chapter 39

Paul M. Ridker, MD, MPH
Eugene Braunwald Professor of Medicine
Harvard Medical School
Director, Center for Cardiovascular Disease Prevention
Divisions of Cardiovascular Disease and Preventive Medicine
Brigham and Women's Hospital
Boston, Massachusetts
Chapter 51

Nina Rieckmann, PhD
Assistant Professor
Department of Psychiatry
Mount Sinai School of Medicine
New York, New York
Chapter 113

Robert Roberts, MD, FRCP(C), FACC, FAHA
President and CEO
University of Ottawa Heart Institute
Director, The Ruddy Canadian Cardiovascular Genetics Centre
Ottawa, Ontario, Canada
Chapters 5, 9, 81

William C. Roberts, MD, DSc, MACC
Executive Director
Baylor University Medical Center
Editor in Chief
The American Journal of Cardiology
Editor in Chief
Baylor University Medical Center Proceedings
Dallas, Texas
Chapter 88

Jose F. Roldan, MD, FACR
Assistant Professor of Medicine
University of Texas Health Science Center at San Antonio
South Texas Health Care System
Rheumatologist
Director, UTHSCA Lupus and Vasculatic Clinic
San Antonio, Texas
Chapter 88

Thom W. Rooke, MD
Professor of Medicine
Mayo Clinical College of Medicine
John and Posy Krehbiel Professor of Vascular Medicine
Gonda Vascular Center
Division of Cardiovascular Diseases
Mayo Clinic
Rochester, Minnesota
Chapter 108

Eric A. Rose, MD
Chairman, Department of Surgery
Columbia University
New York Presbyterian Hospital
Columbia University Medical Center
New York, New York
Chapter 27

Lewis J. Rubin, MD
Professor of Medicine
University of California at San Diego School of Medicine
University of California at San Diego Medical Center
San Diego, California
Chapter 71

Cyril Ruwende, MBChB, MSc, DPhil, FACC
Assistant Professor
University of Michigan
General and Interventional Cardiologist
Michigan Heart PC
Ann Arbor, Michigan
Chapter 58

Joseph F. Sabik, 3rd, MD
Department of Thoracic and Cardiovascular Surgery
The Cleveland Clinic
Cleveland, Ohio
Chapter 65

Robert E. Safford, MD, PhD
Barbara Woodward Lips Professor of Medicine
Mayo Clinic College of Medicine
Consultant in Cardiovascular Diseases
Mayo Clinic, Jacksonville
Jacksonville, Florida
Chapter 99

Allen Mark Samarel, MD
William B. Knapp Professor of Medicine and Physiology
Loyola University Chicago Stritch School of Medicine
Director of Research, The Cardiovascular Institute
Loyola University Medical Center
Maywood, Illinois
Chapter 6

Heinrich R. Schelbert, MD
The George V. Taplin Professor
Department of Molecular and Medical Pharmacology
David Geffen School of Medicine
University of California, Los Angeles
Los Angeles, California
Chapter 23

John S. Schroeder, MD
Professor of Medicine
Stanford University School of Medicine
Stanford, California
Chapter 27

Steven P. Schulman, MD
Professor of Medicine
Department of Medicine
The Johns Hopkins University School of Medicine
Director, Coronary Care Unit
Johns Hopkins University
Baltimore, Maryland
Chapter 101

James B. Seward, MD, FACC
Mayo Clinic
Rochester, Minnesota
Chapter 3

Pravin M. Shah, MD, MACC
Medical Director and Chair
Hoag Heart Valve Center
Hoag Heart Institute
Newport Beach, California
Chapter 78

Prediman K. Shah, MD, FACC
Professor of Medicine
David Geffen School of Medicine at UCLA
Los Angeles, California
Shapell and Webb Chair and Director
Cardiology and Atherosclerosis Research Center
Cedars-Sinai Medical Center
Los Angeles, California
Chapter 52

James A. Shaver, MD
Professor of Medicine
University of Pittsburgh Medical Center
Cardiovascular Institute
Director of C-V Fellowhip Program
UPMC Presbyterian-Shadyside
Pittsburgh, Pennsylvania
Chapter 12

Leslee J. Shaw, PhD
Acting Professor
Division of Cardiology
Department of Medicine
Cedars-Sinai Research Institute
Cedars-Sinai Medical Center
Los Angeles, California
Chapters 19, 64

Daichi Shimbo, MD
Assistant Professor of Medicine
Department of Medicine
Columbia University College of Physicians and Surgeons
New York, New York
Chapter 113

Mark E. Silverman, MD, MACP, FRCP, FACC
Emeritus Professor of Medicine
Emory University
Chief of Cardiology
Fuqua Heart Center of Atlanta
Piedmont Hospital
Atlanta, Georgia
Chapters 1, 12

Andrew L. Smith, MD
Associate Professor of Medicine
Emory University
Director, Emory Center for Heart Failure Therapy and
Transplantation
Emory Clinic—Emory Hospital
Atlanta, Georgia
Chapter 93

Sidney C. Smith, Jr., MD, FACC, FAHA, FESC
Professor of Medicine
Director, Center for Cardiovascular Science and Medicine
Division of Cardiology
Department of Internal Medicine
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina
Chapter 91

Joaquin Solis, MD
Physician
Department of Cardiology
University of Wisconsin Medical School Milwaukee Clinical Campus
Milwaukee, Wisconsin
Chapter 110

Edmund H. Sonnenblick, MD, FACC
The Edmond J. Safra Professor of Medicine
Department of Medicine
The Albert Einstein College of Medicine
Attending Cardiologist and Chief Emeritus
Division of Cardiology
Weiler Hospital for the Montefiore Medical Center
Bronx, New York
Chapter 24

Albert Starr, MD
Director of Academic Affairs
Providence Health System of Oregon
Director, Heart Institute
Providence St. Vincent Hospital
Portland, Oregon
Chapter 79

William G. Stevenson, MD
Professor of Medicine
Harvard Medical School
Director, Clinical Cardiac Electrophysiology Program
Brigham and Women's Hospital
Boston, Massachusetts
Chapter 44

Lisa M. Sullivan, PhD
Associate Professor of Biostatistics
Boston University
Boston, Massachusetts
Chapter 2

Qinghua Sun, MD, PhD
Assistant Professor
School of Public Health
Department of Internal Medicine
Ohio State University
Columbus, Ohio
Chapter 104

Panagiotis N. Symbas, MD
Professor of Cardiothoracic Surgery
Emory University School of Medicine
Professor of Cardiothoracic Surgery
Emory University Affiliated Hospitals
Atlanta, Georgia
Chapter 97

A. Jamil Tajik, MD
Chair, Cardiovascular Diseases
Mayo Clinic College of Medicine
Rochester, Minnesota
Chapters 3, 30

W. H. Wilson Tang, MD, FACC
Assistant Professor in Medicine
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
Staff Physician
Department of Cardiovascular Medicine
The Cleveland Clinic
Cleveland, Ohio
Chapter 24

Anne L. Taylor, MD
Professor of Medicine/Cardiology
Associate Dean for Faculty Affairs
Co-Director, Deborah E. Powell National Center of Excellence in Women's Health
Division of Cardiology
University of Minnesota
Minneapolis, Minnesota
Chapter 103

Usha B. Tedrow, MD, MS
Director, Women and Arrhythmias Program
Brigham and Women's Hospital
Instructor in Medicine
Harvard Medical School
Boston, Massachusetts
Chapter 44

Gaetano Thiene, MD, FRCP, Hon.
Full Professor, Pathology
Cardiovascular Pathology
Institute of Anatomic Pathology
University of Padua
Civil Hospital
Padua, Italy
Chapter 28

E. Murat Tuzcu, MD
Professor of Medicine
The Cleveland Clinic Lerner College of Medicine
Staff, Interventional Cardiologist and Vice Chairman
Department of Cardiovascular Medicine
Division of Medicine
The Cleveland Clinic Foundation
Cleveland, Ohio
Chapter 18

Ramachandran S. Vasan, MD, DM, FACC
Associate Editor, Circulation
Professor of Medicine
Co-Director of Echocardiography Vascular Laboratory
Boston University School of Medicine
Framingham Heart Study
Framingham, Massachusetts
Chapter 2

Stephen F. Vatner, MD
University Professor and Chair
Department of Cell Biology and Molecular Medicine
Director, Cardiovascular Research Institute
University of Medicine and Dentistry of New Jersey
New Jersey Medical School
Newark, New Jersey
Chapter 54

Pugazhendhi Vijayaraman, MD
Director, Cardiac Electrophysiology
Geisinger Wyoming Valley Medical Center
Wilkes-Barre, Pennsylvania
Chapter 40

Renu Virmani, MD
Medical Director
CVPath
International Registry of Pathology
Gaithersburg, Maryland
Chapter 57

Scott Visovatti, MD
Chief Medical Resident
University of Michigan
Ann Arbor, Michigan
Chapter 58

John H. K. Vogel, MD
Chairman
Cardiology
Santa Barbara Cottage Hospital
Santa Barbara, California
Chapter 114

Albert L. Waldo, MD
The Waler H. Pritchard Professor of Cardiology
Professor of Medicine
Case Western Reserve University
Divison of Cardiology
Cleveland, Ohio
Chapter 37

Bruce F. Waller, MD
Cardiologist
The Care Group, LLC
Indianapolis, Indiana
Chapter 55

Richard A. Walsh, MD, FACC, FAHA
John H. Hord Professor
Chair, Department of Medicine
Case Western Reserve University
Physician-in-Chief
University Hospitals of Cleveland
Cleveland, Ohio
Chapters 4, 6

William S. Weintraub, MD
Professor Emeritus
Emory University
Professor of Medicine
Jefferson University
Philadelphia, Pennsylvania
Professor of Health Sciences (Adjunct)
University of Delaware
Chief, Section of Cardiology
Christiana Care Health System
Newark, Delaware
Chapter 111

Paul W. Wennberg, MD
Assistant Professor of Medicine
Gonda Vascular Center
Mayo Graduate School of Medicine
Consultant, Cardiovascular Diseases
Division of Cardiovascular Diseases
Mayo Clinic
Rochester, Minnesota
Chapter 108

Arno (Andy) Wessels, PhD
Associate Professor
Department of Anatomy and Cell Biology
Cardiovascular Develpmental Biology Center
Department of Pediatrics
Division of Pediatric Cardiology
Medical University of South Carolina
Charleston, South Carolina
Chapter 8

James A. White, MD
Co-Director of Cardiovascular MRI
Division of Cardiology
London Health Sciences Centre
London, Ontario, Canada
Chapter 21

Priv. Doz. Dr. Christian Wolpert, MD
Associate Professor
University Hospital Mannheim
Faculty of Medicine of the Ruprecht-Karls-University of Mannheim
Mannheim, Germany
Chapter 46

Charles F. Wooley, MD
Professor of Medicine Emeritus
Division of Cardiology
Department of Internal Medicine
The Ohio State University
Heart Lung Research Institute
Columbus, Ohio
Chapter 1

Jackson T. Wright Jr., MD, PhD
Professor of Medicine
Director, Clinical Hypertension Program
Division of Nephrology and Hypertension
Program Director, General Clinical Research
Case Western Reserve University
University Hospitals of Cleveland
Cleveland, Ohio
Chapter 70

YingXing Wu, MD
Postdoctoral Fellow
Medical Data Research Center
Providence Health and Services
Portland, Oregon
Chapter 79

Jay S. Yadav, MD
Chairman, Center for Medical Innoculation
Director, Vascular Intervention
The Cleveland Clinic
Cleveland, Ohio
Chapter 107

Gan-Xin Yan, MD, PhD
Associate Professor of Medicine
Jefferson Medical College of Thomas Jefferson University
Attending Cardiologist, Director of Basic Research
Main Line Health Heart Center
Wynnewood, Pennsylvania
Chapter 43

Eric H. Yang, MD
Assistant Professor of Medicine
Director of the Coronary Care Unit
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina
Chapter 60

Edward T.H. Yeh, MD
Professor and Chairman
Department of Cardiology
The University of Texas M.D. Anderson Cancer Center
Cardiology Department
Houston, Texas
Chapter 89